CRISPR Consulting

benefits.

CRISPR Strategy Design

A key step of any CRISPR experiment. We know the potential pitfalls.

Optimized gRNA Selection

Use of tools providing better gRNA efficiency predictions.

Sequence Verification

Of gRNA target sites, homology arms and constructs. Avoids bad surprises.

the consulting service.

Do-it-yourself CRISPR is difficult and hands-on experience is invaluable. Successful CRISPR editing requires a thoughtful design, including gRNA selection, and an awareness of the pitfalls that can derail your project.
Leveraging our extensive experience doing diverse CRISPR experiments, we can help you reach your CRISPR goals: we can evaluate your strategy, design your strategy from scratch, generate the required reagents and, if desired, of course also perform the editing.

our consulting options include.

  • evaluate your CRISPR design
  • check your existing donor constructs and gRNAs
  • design your CRISPR strategy
  • select gRNAs with specialized bioinformatic web tools (not CRISPR Optimal Target Finder)
  • ssODN designs for smaller edits
  • provide annotated sequences
  • test gRNAs in vivo
  • clone your gRNAs and donors in your preferred vectors (sequence-verified)
  • clone into our in-house vectors with backbone markers for easy detection of vector backbone insertions (backbone insertions are a common and serious problem in any CRISPR editing)

how does it work.

In case you are interested just send us an e-mail and describe your project and what consulting you would like to have. We will then get into contact with you, discuss open points and then send you a quote.